Integrating a CRM with Magento 2 is a great way to manage customer relationships more effectively. Popular CRM systems like Salesforce, Zoho, and HubSpot offer extensions for seamless integration. These tools help in tracking customer interactions and managing sales pipelines. One challenge to watch for is ensuring that data syncs correctly between systems. Solutions like magento shipping from Amasty can help automate processes within Magento, including customer data management, which might reduce some of the manual work required.